Updated: Jul 29, 2026
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| Certification Vendor: | American Society for Microbiology (ASM) - American College of Microbiology |
| Exam Name: | ABMM Certification Examination (American Board of Medical Microbiology) |
| Exam Number: | ABMM |
| Exam Format: | Written Examination, Oral Examination (may be required depending on candidate pathway), Credential/Document Review |
| Available Languages: | English |
| Related Certifications: | American Board of Medical Laboratory Immunology (ABMLI) |
| Sample Questions: | American Society of Microbiology ABMM Sample Questions |
| Exam Way: | In-person examination (location varies; administered under ASM certification program policies). |
| Pre Condition: | Doctoral degree (PhD, MD, or equivalent) in microbiology or a related biomedical field, plus relevant clinical microbiology training/experience. |
| Section | Objectives |
|---|---|
| Topic 1: Laboratory Management & Quality Systems | - Quality assurance and quality control
|
| Topic 2: Clinical Microbiology | - Virology
|
| Topic 3: Laboratory Operations | - Diagnostic workflow
|
| Topic 4: Infectious Disease Principles | - Pathogenesis
|
1. A researcher is studying the genetic relatedness of different isolates of Mycobacterium tuberculosis. Which of the following molecular typing methods provides the highest discriminatory power for distinguishing between closely related strains?
A) Spoligotyping
B) Restriction fragment length polymorphism (RFLP) analysis
C) Pulsed-field gel electrophoresis (PFGE)
D) Whole-genome sequencing (WGS)
2. A clinical microbiology laboratory is using isothermal nucleic acid amplification techniques for rapid detection of Mycobacterium tuberculosis in sputum. Compared to conventional PCR, isothermal methods offer the advantage of:
A) The ability to simultaneously amplify multiple targets in a single reaction.
B) Higher sensitivity and specificity for detecting low levels of target DNA.
C) Easier integration with downstream analysis techniques such as Sanger sequencing.
D) Faster reaction times and the ability to be performed without sophisticated thermocyclers.
3. A microbiology laboratory receives a corneal scraping from a patient with keratitis. Microscopic examination with calcofluor white stain reveals the presence of septate hyphae and conidiophores with a foot cell and phialides. The MOST likely genus is:
A) Mucor
B) Rhizopus
C) Aspergillus
D) Candida
4. A clinical microbiology laboratory encounters a Gram-negative bacillus isolated from a bloodstream infection. The isolate exhibits resistance to multiple antibiotics, including carbapenems. Further phenotypic testing reveals the production of a metallo-beta-lactamase (MBL). Which of the following antibiotic combinations might still retain activity against this isolate?
A) Ceftazidime-avibactam
B) Aztreonam-avibactam
C) Piperacillin-tazobactam
D) Aztreonam
5. A clinical microbiology laboratory is implementing whole-genome sequencing (WGS) for enhanced surveillance of Listeria monocytogenes isolates associated with foodborne outbreaks. WGS provides several advantages over traditional subtyping methods like pulsed-field gel electrophoresis (PFGE). Which of the following is the MOST significant advantage of WGS in this context?
A) Lower cost per isolate compared to PFGE.
B) Higher discriminatory power for resolving phylogenetic relationships and identifying outbreakclusters.
C) Easier standardization and inter-laboratory comparison of data.
D) Faster turnaround time for obtaining results.
Solutions:
| Question # 1 Answer: D | Question # 2 Answer: D | Question # 3 Answer: C | Question # 4 Answer: D | Question # 5 Answer: B |
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