Last Updated: Jun 16, 2026
No. of Questions: 200 Questions & Answers with Testing Engine
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1. A 26-year-old man with type 1 diabetes mellitus attended a carbohydrate-counting course to facilitate tighter glucose control. He estimated that his carbohydrate ratio was 1:10 and 1 unit correction dose reduced his glucose by 3.0 mmol/L.
He planned to eat a meal containing 50 g of carbohydrate. His pre-meal glucose was 16.0 mmol/L with a target blood glucose of 7.0 mmol/L.
What is the correct dose of bolus insulin (units) that he should administer?
A) 8
B) 10
C) 2
D) 6
E) 4
2. A 50-year-old woman noticed some swelling of her right great toe and a painful right foot. She had type 1 diabetes mellitus of 21 years' duration and recent screening had revealed some mild diabetic retinal changes and peripheral neuropathy.
On examination, she had a hot, red right forefoot with swelling of the great toe. There was callus on the first metatarsal head with a blister beneath it. After de-roofing, the podiatrist probed to a depth of 1 cm. The left foot demonstrated reduced sensation to a 10-g monofilament. Her right foot was 0.6C hotter than the left.
What is the most likely diagnosis?
A) osteomyelitis
B) osteoarthritis
C) necrotising fasciitis
D) gout
E) Charcot's foot
3. A 48-year-old woman presented with a 2-year history of weight gain, easy bruising and
mood disturbance.
Investigations:
fasting plasma glucose6.9 mmol/L (3.0-6.0)
low-dose dexamethasone suppression test (2 mg/day for 48 h):
serum cortisol200 nmol/L (<50)
24-h urinary free cortisol (?3)670, 400 and 300 nmol (55-250)
plasma adrenocorticotropic hormone (09.00 h)25.0 pmol/L (3.3-15.4)
MR scan of pituitarynormal
What test is most likely to give a definitive diagnosis?
A) petrosal sinus sampling
B) CT scan of chest
C) corticotropin-releasing hormone test
D) high-dose dexamethasone suppression text (8 mg/day for 48 h)
E) octreotide scan
4. A 58-year-old man presented with tiredness and breathlessness. He had been treated for type 2 diabetes mellitus and hypertension for the past 10 years. He was free of complications. His current medication included ramipril 10 mg daily, rosuvastatin 10 mg daily, metformin 500 mg three times daily, dapagliflozin 10 mg once daily and exenatide 10 micrograms twice daily.
On examination, his body mass index was 36 kg/m2 (18-25).
Investigations:
haemoglobin93 g/L (130-180)
MCV110 fL (80-96)
white cell count3.6 ? 109/L (4.0-11.0)
platelet count140 ? 109/L (150-400)
reticulocyte count0.5% (0.5-2.4)
serum ferritin250 ug/L (15-300)
serum vitamin B1240 ng/L (160-760)
serum folate3.0 ug/L (2.0-11.0)
Which medication is most likely to be contributing to his anaemia?
A) metformin
B) rosuvastatin
C) dapagliflozin
D) ramipril
E) exenatide
5. A 45-year-old woman attended for annual follow-up for long-standing hypoparathyroidism (a complication of thyroid surgery 5 years previously). She was asymptomatic. She was taking alfacalcidol 1 microgram daily.
Examination was unremarkable.
Investigations:
serum creatinine105 umol/L (60-110)
serum corrected calcium2.45 mmol/L (2.20-2.60)
24-h urinary calcium9.8 mmol (2.5-7.5)
What is the most appropriate next step in management?
A) recommend low-calcium diet
B) change alfacalcidol to teriparatide
C) change alfacalcidol to calcitriol
D) add bendroflumethiazide
E) decrease alfacalcidol dosage
Solutions:
| Question # 1 Answer: A | Question # 2 Answer: A | Question # 3 Answer: A | Question # 4 Answer: A | Question # 5 Answer: E |
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